For some reason, if you decide you don’t want users to use Safe Mode, here is a way to disable access.
1. Open the Registry Editor (Start > Type regedit and press enter.
2. Navigate to HKEY_LOCAL_MACHINESYSTEMCurrentControlSetControlSafeBoot.
3. Rename the Minimal and Network subkeys to Minimal.old and Network.old.
4. Reboot, and you will not be able to access Safe Mode by pressing F8